الفهرس | Only 14 pages are availabe for public view |
Abstract The present study was designed into two main stages, Stage I, 50 native breed adult goats were used as donors for bone grafts. Clean harvesting method was used for collection of bone grafts followed by autoclave sterilization (121°C ⁄ 30 minutes). The feasibility of the banked bone was assessed through radiographic examination. Also the handling characteristics were estimated for up to 6 months post- retrieval. The results revealed that the bone bank should be replenished after 3 months. Stage II, included 20 dogs; these dogs were subjected to an artificial induction of femoral defects (3 cm length). The induced defects were reconstructed with ACXG (16 dogs) and FCAG (4 dogs). The operated dogs were observed for up to 12 months through clinical and radiological examinations. After euthanasia the harvested femurs were examined morphohistologically. The obtained results showed that the use of autoclaving as a method of sterilization has several advantages in terms of simplicity, efficiency and economy. The clinical, radiological and morphohistological evaluations during the course of 12 months confirmed acceptance of ACXG in similar manner to FCAG in reconstruction of experimentally induced femoral defects. |