الفهرس 
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Abstract
Study the effect of iron overload on blood homeostasis as well as oxidative
stress that may be induced in liver tissue and evaluate the protective and antioxidant
properties of the aqueous extracts of green tea or licorice. Using the experimental iron
overload model in the present work has demonstrated a positive correlation between
free iron and the formation of oxidative damage in liver tissue. The consequence of
such damage provides an account of some of the initiating factors or early events in
hepatocellular damage that may lead to the pathological manifestations and
biochemical changes (elevated lipid profile and impaired both kidney and liver
functions) observed in chronic iron overload conditions. The eo administration of the
two tested extracts with excess iron elicited a lowering effect on lipid peroxide
product (MDA); the more potent lowering effect was displayed by licorice extract.
The concomitant oral administration of green tea and licorice aqueous extract elicited
protective effects indicated by the recovery that induced in both liver and kidney
functions as well as the reduction of lipid profile. Green tea and licorice aqueous
extracts in iron overloaded rats were not seemed to be effective on hepatic antioxidant
enzymes (GSHPx and total SOD). However licorice extract administration evoked a
mild elevation in hepatic GSH content.