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Abstract In this study, we studied the role of mfVEP in evaluating cases of ocular hypertension converting into early POAG in correlation with the results of SAP. It was found that mfVEP is more sensitive than SAP in detecting early glaucomatous changes in ocular hypertension patients. Latency of mfVEP was found to be more sensitive than amplitude. Both mfVEP amplitude and mfVEP latency showed significant abnormal changes in localized sectors that appeared to be normal when first tested by SAP, but later on it became relatively significant scotoma on SAP. On the other hand, some patients had significant abnormal changes in mfVEP amplitude and mfVEP latency, but they continued to have a normal SAP after follow up. This could be either that these changes will appear on SAP but after longer period of follow up, and then it confirms the higher sensitivity of the mfVEP. But also it can be a false alarm of false positive test, and then this will mean a lower specificity of mfVEP than SAP. Clinically, mfVEP was easier for the patient to perform, as it as an objective technique which does not need an active interaction from the patient as compared to the subjective SAP. This makes it easier to obtain mfVEP results from the first test done by the patients with no need for repetition to have better learning curve and reliable test as with SAP. Two time‐ consuming steps were met in this study, which are the preparation of the patient and data analysis. 78 from this study, we deducted that mfVEP can be of valuable role in early detection of glaucomatous changes in ocular hypertension patients with normal SAP results. Patients with mfVEP changes may need closer monitoring and follow up with more frequent SAP examination. Further studies about mfVEP may help for better understanding of this new advanced technique and are recommended to complete the evaluation of the specificity and accuracy of mfVEP. Also, more progression of mfVEP testing machine is needed to save time and to make data interpretation and analysis easier and more accurate. |