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العنوان
COMPARISON OF DIFFERENT DIAGNOSTIC METHODS IN CASES OF BRUCELLOSIS AT FAYOUM FEVER HOSPITAL
المؤلف
Ahmed Gomaah,Samy
الموضوع
Haematological Changes.
تاريخ النشر
2010 .
عدد الصفحات
104.P؛
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
علم الأوبئة
تاريخ الإجازة
1/1/2010
مكان الإجازة
جامعة عين شمس - كلية الطب - Tropical Medicine
الفهرس
Only 14 pages are availabe for public view

from 104

from 104

Abstract

B
rucellosis is a well documented cause of fever of unknown origin with varied and non specific symptoms. In addition to fever, other prominent symptoms including sweating, malaise, anorexia, fatigue, weight loss and depression may by present. The diagnosis of brucellosis should be considered in an individual with otherwise unexplained chronic fever and nonspecific complaint. Such patients should be questioned for possible sources of exposure to brucella including contact with animal tissues or ingestion of unpastuerized milk or cheese. Both cultures and serologic tests are used to establish the diagnosis of brucellosis. Ideally, the diagnosis of brucellosis is made by isolation of the organism from cultures of blood
The aim of this work was to compare the different diagnostic tests-blood culture, ELISA, Slide and Tube Agglutination- in diagnosis of brucellosis
Forty patients were enrolled in this study were and divided into two groups on the basis of manifestations of brucellosis and positivity of slide agglutination test, as follow:
Group (1), included twenty patients with present history suggestive of brucellosis but their slide agglutination test was negative (less than 1/160) and Group (2), included twenty patients with positive slide agglutination (more than 1/160). All patients were subjected to: Brucella agglutination test (slide and tube), ELISA for Brucella Antibodies IGg type and blood culture for Brucellosis
The results of current study showed that the blood culture was positive in 30% of patients with positive slide and tube agglutination tests and none of the patients with negative slide and tube agglutination tests. The results of the slide agglutination test were exactly the same as the tube agglutination test.
In the current study there was no statistically significant difference between the results of ELISA and slide agglutination test or standard agglutination tests. The ELISA test was positive in 90% of patients with positive agglutination tests and was negative in 100% of cases with negative agglutination tests.