الفهرس 
Chronic obstructive pulmonary disease(COPD)
Stages of COPDOnly 14 pages are availabe for public view
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Abstract
Background: BBLVR treatment could be done by administration of a hydrogel or autologous blood that flows into the alveolar compartment which called biological lung volume reduction.
Methods: Thirty patients admitted in chest department with emphysematous bulla or bullae were recruited in the study. bronchoscope was introduced through nostril or endotracheal tube in case of general anesthesia. Bronchoscope was administrated till reach the most affected subsegments recognized by high resolution CT chest, bronchoscope was advanced into wedge position then 10 ml of autologous blood and cyclokapron followed by gel foam instilled through working channel of the bronchoscope.
Results: significant difference between RV before and after BBLVR, the mean RV before BBLVR was 128±6.7% while after BBLVR it was 117±4%.Also there was a highly significant rise of 6MWT after BBLVR, the FEV1 shows a highly significant rise after BLVR .The median MMRC dyspnea score after BBLVR was 3, while it was equal to 2 before BBLVR.
Conclusions: results indicate that BBLVR can be safe and may produce benefits in appropriately selected patients with advanced emphysematous bulla.