الفهرس | Only 14 pages are availabe for public view |
Abstract In this study 76 clinically diagnosed cases of ASOM of all age groups and both the sexes attending the otolaryngology outpatient clinic, faculty of medicine, Cairo University -#102;-#114;-#111;-#109; February to August 2009 were studied. Samples were aspirated aseptically -#102;-#114;-#111;-#109; patients by syringes after cleaning the external ear canal. Bacteria were isolated -#102;-#114;-#111;-#109; samples cultures and then were identified by standard biochemical reactions. br Antibiotic susceptibility testing was done by Kirby-Bauer disc diffusion method. Then plasmid curing was carried out to compare the bacterial resistance before and after curing to find out if the resistance mechanism was chromosome mediated or plasmid mediated. br Results: br Staphylococcus aureus was the predominant organism followed by Streptococcus pneumoniae. The antibiotics Ciprofloxacin, Cefotaxime, and Amoxyclav showed higher activity against bacteria than Amoxicillin and Ampicillin. Resistance of Staphylococcus aurues to Amoxicillin, Amoxyclav, and Cefotaxime was plasmid mediated while its resistance to Ampicillin and Cirofloxacin was chromosome mediated, and resistance of Streptococcus pneumoniae to Ampicillin and Amoxyclav was plasmid mediated, -#119;-#104;-#101;-#114;-#101;as its resistance to Amoxicillin, Cefotaxime, and Ciprofloxacin was chromosome mediated. |