الفهرس 
AcknowledgementOnly 14 pages are availabe for public view
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Abstract
Cessation of menstruation is considered as the cardinal symptom of
menopause, endometrium normally undergoes a gradual atrophy, starting with
an inactive phase in which neither proliferation nor secretion is present and
ending up as a thin layer, often riddled with cystic cavities lined by a cuboidal
or flat epithelium, in which the organelles are pushed to random locations and
the stroma becomes fibrotic.
The normal postmenopausal endometrium is atrophic, appearing as a
thin echogenic line. The endometrium normally measures 5mm or less (double
layer) in anteroposterior diameter in postmenopausal women who are not
receiving Hormone Replacement Therapy.
This study has been conducted on 300 menopausal women to evaluate the
relationship between endometrial thickness and body mass index in
asymptomatic women . We used transvaginal ultrasonound in studying the
endometrial thickness in cases of asymptomatic postmenopausal women with
histopathologic endometrial studying of these cases.
Body mass index is measured for all cases as the individual’s body
weight divided by the square of her height.
Summary and Conclusion
79
In the present study the age of onset of menopause ranging from 55-65
years with a mean of 59.95 years and a S.D +3.73 years and the years of age
since menopause ranging from 5 -15 years with a mean of 9.95 years and S.D of
± 3.73. The thickness of the endometrium ranges from 3-8mm with a mean of
5.85 mm and S.D + 0.640 .The body mass index ranges from 21.2 – 46.7Kg/m2
with a mean of 28.74 Kg/m2 and S.D + 6 .
A negative correlation was found between age and endometrial thickness
(r = -0.224, p: <0.05).The results have shown also a negative correlation
between endometrial thickness and the years since menopause (r= - 2.84, p: <
0.01). But it was found that BMI was positively correlated with endometrial
thickness according to the results(r=0.841, p: <0.001).
So, There is a strong relationship between endometrial thickness and
Body Mass Index, regardless the age of female and years since menopause.
Five mm endometrial thickness is recommended as a cut off value
below which endometrial abnormalities could be excluded and above it
endometrial abnormalities to be expected with the need for using other
diagnostic complementary technique as histopathologic evaluation to establish
the diagnosis.
Two hundred &eighty eight cases was found equal or less than 5mm, and
12 cases more than 5 mm for which endometrial sampling was done, 10 cases (
83.3%) revealed a picture of atrophic endometrium, only one case (8.3%) of
chronic endometritis , and 1 case (8.3%) revealed a picture of endometrial
polyp.
Summary and Conclusion
80
Conclusion:
There is positive relationship between BMI and endometrial thickness in
asymptomatic postmenopausal females.
Screening studies over larger groups of obese asymptomatic
postmenopausal women is recommended.