الفهرس 
Staging of breast cancerOnly 14 pages are availabe for public view
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Abstract
B
reast conserving therapy has become a standard treatment option for patients with early stage breast cancer with low rates of local recurrence and good cosmetic outcome.
Patient selection is important since not all patients would benefit, particularly those with features of their cancer that would increase the risk for a later breast recurrence requiring mastectomy.
Many risk factors for local recurrence after breast conserving surgery have been studied widely .the most established risk factors are young age, positive resection margins, multicentric disease and vascular invasion. Extensive intraductal component has been much discussed as a risk factor, but seems to have little prognostic value if negative margins can be obtained.
We have shown LR rates comparable to those in other series. Radiation therapy was given adequately and did not influence the local relapse rate.
The majority of recurrences detected were true or marginal recurrences, which arise mostly in the first 4 years after BCT.
Follow-up of patients after BCT seems necessary certainly in these years. LR risk decreases gradually with increasing age, which makes it necessary to take in account the patient’s age with the other known risk factors for LR, such as histopathological positive margins, to decide if a patient is suitable for breast-conserving therapy.
Several recent studies have shown the importance of breast magnetic resonance imaging for detection of recurrent lesions in patients treated with conservative surgery.
Local recurrence that develop after breast conservation therapy should be managed carefully, as long term survival can frequently be achieved.
Finally, breast conservative therapy is an appropriate primary therapy for early breast cancer, but it is necessary to take in account the patient’s age with the other known risk factors for LR, such as histopathological positive margins, breast size, tumor size & the adequacy of radiotherapy to decide if a patient is suitable for breast-conserving therapy.