الفهرس 
THYROID GLANDOnly 14 pages are availabe for public view
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Abstract
Thyroid hormones act on almost organs throughout the body and regulate the basal metabolism of the body. Digestive symptoms and signs may also reveal clues to thyroid diseases, when ignored or underestimated, diagnosis may be delayed and serious consequences may occur. Gastrointestinal motor dysfunction has been widely accepted as the main cause of symptoms of gastrointestinal in hypothyroidism. Hypothyroidism manifests through the body with decrease metabolic function. It is biochemical characterized by accumulation of glycosaminoglycans mainly hyaluronic acid in soft tissue, interstitial tissue and muscles.Gastric dysmotility is significant more frequent in hypothyroidism and this is result of muscles edema and altered myoelectrical activity. Helicobacter pylori infection is a common infection of gastrointestinal tract. There was an association between hypothyroidism and helicobacter pylori. The monoclonal antibodies against Cag A positive H.pylori strains has cross react with follicular cells of thyroid gland.
In this study the results showed that EGG parameter have changed in hypothyroid patients compared to normal subjects (controls), but it was statistically insignificant.
The power ratio and visual analysis were the most reliable parameters for evaluation gastric dysmotility by EGG.
A high prevalence of helicobacter pylori infection in hypothyroid patients of our study. The frequency and percentage of infection was 62.5%in cases higher than controls was 25%.
There was statistical significant difference of helicobacter pylori titer, weight and BMI between cases and controls.
Conclusion:
from the present study we concluded:
EGG parameter have changed in hypothyroid patients in the form of tachygastria, bradygastria, decrease in the power ratio and dominant frequency (DF) due to change in gastric electrical activity. This is consider as the reason of GIT disturbance in hypothyroidism.
There was increase of the rate at helicobacter pylori infection in hypothyroidism.