الفهرس | Only 14 pages are availabe for public view |
Abstract The attribution of a haemolytic element to the anaemia in bilharziasis was proposed by many investi- gators. Erythrocyte sequestration in an enlarged bil- harzial spleen, membrane alterations due to coating of the red cells with immunoglobulins and modulation of haemoglobin type by the schistosoma worm were all mechanisms postulated to explain the shortened red cell life span found in schistosomiasis. The hypothesis that the anaemia in schistoso_ miasis might in part be related to a lesion of the erythrocyte membrane or the enzymes of the red cells leading to shortened red cell life span was studied in the present work. The study comprised 75 subjects, 25 as normal controls and 50 patients represented different groups hepatosplenic schistosomiasis. The bilharzial patients were divided into five groups I: Group of early active intestinal schistoso_ miasis. II: Hepatomegalic group. Hepatosplenomegalic group. IV: Splenomegalic group. V: Group of advanced hepatic fibrosis with ascites. |