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العنوان
Biological studies on the effect of some
Egyptian medicinal plants in irradiated rats
المؤلف
Khairy Mohamed Abdel-Rafei,Mohamed
هيئة الاعداد
باحث / Mohamed Khairy Mohamed Abdel-Rafei
مشرف / Amina Mohamed Medhat
مشرف / Soheir Abdel Azim Osman
مشرف / Dina Mohamed Seoudi
الموضوع
The Inflammatory Mediators.
تاريخ النشر
2009.
عدد الصفحات
221.p؛
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
Analytical Chemistry
تاريخ الإجازة
1/1/2009
مكان الإجازة
جامعة عين شمس - كلية العلوم - Biochemistry
الفهرس
Only 14 pages are availabe for public view

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Abstract

In the current experiments, a study of the acute and systemic
anti-inflammatory effects of Origanum majorana L. (O. majorana)
and Artemisia herba alba (A. herba alba) ethanolic extracts has been
investigated. Furthermore, their analgesic, anti-pyretic as well as their
effects on liver and kidney (biochemically and histopathologically)
were examined.
The acute toxicity study (LD50) of both extracts revealed that
O. majorana and A. herba alba ethanolic extracts are quietly safe. No
mortalities were recorded and no abnormal symptoms appeared on
rats of after oral administration of both extracts till 5 g/kg b.wt.
Four main sets of experiments were performed. The first set
was constructed in order to evaluate the anti-inflammatory effects,
whether acute or systemic.
The acute anti-inflammatory effect was evaluated using the
carrageenan induced rat paw oedema. Intraplantar injection of
carrageenan resulted in a pronounced swelling and a significant
increase in the paw volume.