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العنوان
Rotavirus Infection in Infantile Intussusception: Magnitude of the problem
الناشر
Ain Shams University-facultyof medcine.
المؤلف
Emad Fawzy Ahmed
هيئة الاعداد
مشرف / Moustafa Abd EL-Aziz
مشرف / May Fouad Nassar
مشرف / Soha Ezz El-Arab Abd El-Wahab
مشرف / Emad Fawzy Ahmed
تاريخ النشر
2007.
عدد الصفحات
135P؛
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الطب (متفرقات)
تاريخ الإجازة
1/1/2007
مكان الإجازة
جامعة عين شمس - كلية الطب - Pediatrics
الفهرس
Only 14 pages are availabe for public view

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from 201

Abstract

Infection of the gastrointestinal tract are caused by a wide variety of enteropathogens including bacteria, viruses and parasites and the most important cause is the viral one and most important virus is rotavirus. This particular virus has been claimed responsible for cases of intussusception especially that cases were reported following marketing of the rotavirus vaccines.
The aim of the current study was to study the magnitude of the rotavirus infection in gastroenteritis cases complicated with intussusception in comparison with acute uncomplicated gastroenteritis in a trial to delineate the role of rotavirus in occurrence of intussusception.
This prospective study included 61 patients 40 of whom had acute uncomplicated gastroenteritis and the rest were complicated with intussusception. Enrolled cases were subjected to detailed history taking, thorough clinical examination and laboratory investigations including complete stool analysis as well as rotavirus antigen detection in stools by ELISA technique.
In all, 60.0% of cases of the gastroenteritis group were positive to rotavirus antigen while only 41.6% of patients were positive to rotavirus antigen in the intussusception group with no statistically significant difference in between them.
There was no significant difference between both groups as regard age presentation, social level and nutritional history as well as month of presentation.
Watery and offensive stools were statistically more common among gastroenteritis group while offensive and blood stools were more common among intussusception group. No significant differences were detected between both groups as regards clinical examination data yet there was highly significant difference as regards hyperactive bowel sounds which were more common in intussusception.
On comparing the patients who turned positive for rotavirus antigen from both groups no significant differences were found except for the acute abdominal cramps which were statistically more common in rotavirus positive cases in the gastroenteritis group. Additionally, most of rotavirus positive cases among intussusception group were significantly presented either in February or December. On the other hand no statistically significant relation between month of presentation and rotavirus positivity was detected among the gastroenteritis group