الفهرس 
Left main coronary arteryOnly 14 pages are availabe for public view
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Abstract
Significant left main coronary artery stenosis (> 50%) is an important indication for coronary artery bypass grafting (CABG). However, waiting list for surgery may result in increased risk of MACE during the waiting period.
In this study, we aimed to determine the incidence of MACE and the predictors of these events among patients with LMCA stenosis waiting for CABG.
A total of 48 patients with significant LMCA stenosis were included in the study. Basic clinical data, electrocardiographic, echocardiographic and angiographic data were obtained for each patient. Then, these patients were followed up for two months for the occurrence of MACE after coronary angiography, and during waiting for CABG.
The association of acute coronary syndrome with significant LMCA stenosis was a strong predictor of MACE among patients waiting for CABG (ACS in eventful group was 87.6%, while in uneventful group was 25% with P < 0.01. Also, the presence of significant ST segment depression on resting ECG, impaired LVEF (<40%), severe LMCA stenosis (>70%), and significant RCA stenosis were considered important factors for the occurrence of MACE. whereas, risk factors for coronary artery disease, the presence of other vascular disease, the site of LMCA stenosis, the presence of collaterals between LMCA and RCA and time interval between coronary angiography and CABG did not influence the perioperative outcomes among patients with significant LMCA stenosis.
from the results of the study, we concluded that patients with LMCAS presented with acute coronary syndrome, and those with significant ST segment depression, LV systolic dysfunction (<40%), severe LMCA stenosis (> 70%), and with associated significant RCA stenosis should be considered for emergency CABG without delay.