الفهرس 
Diabetes and HeartOnly 14 pages are availabe for public view
 |  | from | 122 |  |  |
| | | from | 122 | | |
Abstract
Patients with diabetes have a markedly increased incidence of adverse cardiovascular events and less favorable outcomes from myocardial infarction or after coronary interventions. In addition to concomitant hypertension and dyslipidemia, increasing evidence suggests that impaired glycemic homeostasis has a direct influence on the formation and propagation of atherosclerotic plaque (Frick et al, 2004).
In this study we aimed to study the impact of blood sugar level during the elective PCI in diabetics on the results of the procedure as regards angiographic outcome, myonecrosis, short term clinical follow up.
This study was conducted on 70 diabetic patients with chronic stable angina. The patients recruited from patients presented to the outpatient clinic for elective PCI in Ain Shams University hospitals with proved ischemic heart disease, defined by previous documented coronary stenosis on cardiac catheterization, or previous invasive cardiovascular revascularization procedure and history of myocardial infarction (more than 3 weeks) who either received or not thrombolytic therapy and excluding patients with lesions failure to cross the lesion with the guide wire , preprocedural elevation of creatine kinase-myocardial band (CK-MB) or major surgical procedure within one week before enrollment.
All patients were subjected to full history taking and physical examination Collecting baseline blood sample for CK-MB at and after the procedure. Data were collected, revised, verified then edited on P.C. The data were then analyzed statistically using SPSS statistical package version.
from the current study we concluded that diabetic patients were more prone to short term complications and myonecrosis. The complications were more related to the level to CK MB elevation. The complications were more related to the level to HbA1c rather than a single blood sugar measurement. The end result of revascularization which was represented by TIMI flow score was not affected by the level of blood sugar.