Search In this Thesis
   Search In this Thesis  
العنوان
Using Different Methods for Identification of Dermatophytes from Clinical Samples and Antifungal Susceptibility Testing /
المؤلف
Azab, Marwa Mohamed.
هيئة الاعداد
باحث / مروه محمد عزب
مشرف / صلاح الدين محمد عبدالله
مناقش / طارق السعيد البنا
مناقش / رمضان حسن ابراهيم حسن
الموضوع
Skin Diseases. Antifungal agents.
تاريخ النشر
2011.
عدد الصفحات
150 p. :
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
الصيدلة ، علم السموم والصيدلانيات (المتنوعة)
تاريخ الإجازة
1/1/2011
مكان الإجازة
جامعة قناة السويس - كلية الصيدلة - الميكروبيولوجى والمناعه
الفهرس
Only 14 pages are availabe for public view

from 170

from 170

Abstract

In a study on importance of dermatophytes infection in Ismailia, a total of 154 patients of different ages and both sex having tinea were examined mycologically. The overall occurrence rates of dermatophytes among the patients clinically showing ringworm lesions were 77.3% and 60.8% by direct microscopy and cultural examinations respectively, with the highest frequency of occurrence was recorded among male young patients aged less than 10 years in comparison with older ones. The isolated dermatophytes were T. violaceum, M. canis, T. rubrum, T. tonsurans, T. verrucosum, T. mentagrophytes, M. gypseum, M. audouinii and E. floccosum. PCR assay, biochemical testing, culturing, and microscopical examination are reliable methods to detect dermatophytes in all tinea forms with the advantage that PCR assays more rapid than cultures and biochemical testing, which need several days. Azoles, especially itraconazoles and ketoconazoles still to be the first choice antifungal agents for the treatment of dermatophytosis. Urea can be used as a fungicide agent, beside its keratolytic action on dermatophytes.
Keywords: Tinea, Dermatophytes, Antifungal agents, Urea.