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Abstract The present study aimed to clarify the effect of boldenone undecylenate on performance and health condition, hematological and some biochemical parameters, histological changes, immune response, sperm quality and effect of withdrawal period on affected parameters. Sixty male apparently healthy New Zealand white rabbits were divided uniformly by weight into three equal groups each of 20 rabbits. Group (1) was injected intramuscularly with adjuvant substance (sesame oil) once every three weeks for 3 times and was considered as a control group. Group (2) was treated with boldenone at the manufactured recommended dose to rabbit (4.5mg/kg BW) once every 3weeks for 3 times. Group (3) was treated with boldenone at a dose double the recommended dose (9 mg/kg BW) once every 3weeks for 3 times. Two blood samples were collected each 15 days from each animal for hemogram the second part for separation of serum and another blood samples were collected monthly on heparin three months and used for evaluation of phagocytic activity of hetrophils. Also liver, kidney, testes and accessory sex organs were collected for histopathology. three semen collection were collected at 30, 45,60 days post last injection . As a final conclusion of the present study, boldenone undecylenate injection induced a significant increase in the growth rate of the treated rabbits in especially in group (D) in comparison with control. Also it was found that boldenone undecylenate improved the feed conversion in the treated groups and the degree of improvement was dose dependant. |