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العنوان
Serum cystatin C for early detection of diabetic nephropathy in patients with type 2 diabetes mellitus /
المؤلف
Aboulaila, Hemmat Abdelnaby Hamed.
هيئة الاعداد
باحث / همت عبدالنبى حامد ابو ليله
مشرف / محسن موسى الدراوى
مشرف / محمد محمد حسان
مشرف / محمد محمد حسان
الموضوع
Cystatins - physiology. Diabetes Mellitus - diagnosis. Internal Medicine.
تاريخ النشر
2012.
عدد الصفحات
118 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الطب الباطني
تاريخ الإجازة
1/1/2012
مكان الإجازة
جامعة الزقازيق - كلية الطب البشرى - الباطنه العامه
الفهرس
Only 14 pages are availabe for public view

from 331

from 331

Abstract

Renal impairment is an important feature of diabetes mellitus, causing a significant morbidity and mortality, and much effort has been devoted to the detection of this complication at a stage when it is silent and potentially reversible.
The protease inhibitor Cystatin C is a non-glycosylated low molecular weight protein. Cystatin C has been proposed to be a marker as it is produced by all nucleated cells at a constant rate and is freely filtered by the glomeruli and completely catabolized in the proximal tubules.
The aim of this study is to evaluate serum cystatin C as a marker of early renal affection in type 2 diabetic patients.
To achieve this goal, this study was performed on 80 type 2 diabetic patients and were compared with 20 healthy subjects of matched age, sex and BMI as a control group.