الفهرس 
INTRODUCTIONOnly 14 pages are availabe for public view
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Abstract
Gastric cancer is one of the frequent causes of cancer-related deaths
especially in the far east.The early detection and preoperative staging of
gastric cancer is critical. Conventional endoscopy and double contrast
barium swallow studies allow the early detection of small lesion but cannot
determine the depth of tumor invasion and the presence or absence of
metestasis.
Early gastic carcinoma is defined as carcinoma limited to the mucosa
or submucosa, irrespective of the presence of lymph node metastasis.
Aim of the work was to evaluate the role of Multi-slice CT in early
detection of gastric carcinoma.
The anatomy and CT anatomy was discussed in this study, as well as
the pathology of gastric carcinoma was reviewed.
Adenocarcinoma is the most common gastric malignancy,
representing over 95% of malignant tumors of the stomach.
The peak prevalence is between 50 and 70 years of age.
The prognosis was based on the extent of gastric wall penetration,
lymph nodes involvement and distant metastases. Adenocarcinoma is an
aggressive tumor with a 5-year survival rate of less than 20%. However,
early gastric cancers are curable lesions, with 5-year survival rates of more
than 90%.
Therefore, early detection and accurate staging of gastric cancer are
essential because surgical resection is the treatment of choice.
Endoscopic ultrasonography (US) provides the most useful
information regarding tumor location, horizontal extension of the tumor,
Summary and Conclusion
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the depth of mural invasion, and perigastric lymphadenopathy. Endoscopic
US allow reliable distinction between an intramural lesion and extrinsic
compression.
Currently, multidetector row CT scanner allows for thinner
collimation and faster scanning, which markedly improve imaging
resolution and enable rapid and easy handling of three- dimensional image
reconstruction of the obtained images. Two-dimensional MPR and CT
gastrography, including virtual gastroscopy and transparency rendering,
provide multiplaner cross-sectional imaging, gastroscopic viewing, and
upper gastrointestinal series imaging in the same data acquisition.
Transparency rendering provides global orientation of the focal
findings in the stomach in the same way as upper gastrointestinal series
imaging.
Early gastric cancer appears as protruding, superficial or depressed
lesion on mucosal layer of stomach.
Multi-slice CT allows noninvasive assessment in distant metastasis
of gastric cancer in the pelvis.
Gastric cancer recurrence has a poor prognosis. Multi-slice
CT is the primary modality of suspected recurrence.
The accuracy for staging gastric carcinoma is 71.4%. The
preoperative multi-slice CT scan had 96.1% sensitivity, 100% specificity
and 96.4% accuracy for evaluating serosal invasion. The sensitivity,
specificity and accuracy for assessing pathologic lymph node involvement
are 73.1, 50.0 and 84.2 %, respectively. But multi-slice CT had 100%
sensitivity for evaluating hepatic metastases.