الفهرس | Only 14 pages are availabe for public view |
Abstract This work is important due to the use of pesticide as well as the use of any potentially injurious chemical substance must be taking into consideration the balance of the benefits that may be expected versus the possible risk of injury to human health or degeneration of environmental quality. The previous issue may be explore an help in establishing the no observed adverse effect levels (NOAE) and the application of a safety factors, there by arriving at an acceptable daily intake(ADI). For genotoxic or carcinogens it is possible to assess the risk at the level at the estimated exposure. On the other hand, the (ADI) approach, which is used for non carcinogens, chemicals, and certain non genotoxic, carcinogens, is intended to estimate a dose that is considered safe in light of the available. 1. Acute medium lethal dose LD50 toxicity :- This study was undertaken to investigate the acute oral administration toxicity of Lamba-cyhalothrin, Profenofos and Chlorpyrifos to adult white mice, the mortality data recorded after 24 hours, the extracted acute LD50 value found to be 76 mg/kg 358 mg/kg and 150 mg/kg for respectively. The results revealed that, the three of tested tested insecticides could be considering as a highly toxic compound according to the classification of the chemical toxic. Meanwhile, Lamba-cyhalothrin is considered highly toxic when compare with Profenofos and Chlorpyrifos are considered slightly toxic. |