الفهرس | Only 14 pages are availabe for public view |
Abstract Living donor liver transplantation has become an excellent treatment method for patients with end-stage liver disease. The optimal outcome of this maneuver lies as much on the venous outflow as on the inflow so optimal venous outflow is critical for its success. Hepatic venous outflow block is occasionally diagnosed intraoperatively on the basis of swelling and congestion of the graft. Intraoperative ultrasonography detects a flat waveform in the hepatic vein. Hepatic venous outflow block detected intraoperatively can usually be relieved by keeping the graft in its original position. Postoperatively, the clinical presentation of HVOB can include ascites, elevated liver function test results, splenomegaly, variceal bleeding, lower-extremity edema, and kidney dysfunction. HOVB can be treated successfully by interventional balloon angioplasty and stent placement. This study evaluates the different techniques of hepatic out flow reconstruction, and their impact on outcome in ٩٠ patients underwent living donor liver transplantation in the National Liver Institute, in the period starting from April ٢٠٠٣ till June ٢٠١٠. They were ٦٩ (٧٦.٦%) males & ٢١ (٢٣.٤%) females, ٢٣ (٢٥.٥%) of them were Children (≤١٨ years of age) & ٦٧ (٧٤.٥%) were adults (>١٨ years). In pediatric recipients: we used left lateral segment (segment II & III) in ١٦ cases (٦٩.٥%), Left lateral segment with partial part of segment IV in ٣ cases (١٣%), left lobe including MHV in ٣ cases (١٣%) and right lobe in one case (٤.٣%). In adult recipients: we used right lobe without MHV in ٦٠ cases (٨٩.٦%) [in ٨ cases significant tributaries for MHV was present in the liver graft so it was reconstructed] & right lobe with MHV in ٧ cases (١٠.٤%). Summary------------------------------------------------------------------------------------------- ------------------------------------------------- ١ ١ ٨ ------------------------------------------------ The venous drainage was as following in grafts for pediatric recipients: LHV only was present in ١٢ grafts (٥٢.٣%). LHV & MHV was included (separately) in ٢ grafts (٨.٦%). RHV in one graft (٤.٣%) (Rt lobe graft was implanted in case No. ٨٩). Separate opening for segment II & segment III Veins in ٧ grafts (٣٠.٥%). Common trunk for LHV & MHV in one graft (٤.٣%). In grafts for adult recipients: RHV only was present in ٣١ grafts (٤٦.٢%). RHV+IRHV in ١٦ grafts (٢٣.٩%). RHV+V٥ in ٤ grafts (٦%). RHV+V٨ in ٢ grafts (٣%). RHV+V٥+V٨ in ٢ grafts (٣%). RHV+V٥+IRHV in one graft (١.٥%). RHV+V٨+IRHV in ٢ grafts (٣%). RHV+IRHV+PRHV in ٢ grafts (٣%). RHV+MHV+IRHV in ٧ grafts (١٠.٤%). The venous grafts was used only in the adult group in ١٦ hepatocaval anastomosis (٢٣.٩%) which was in the form of interposition venous graft in ١٤ anastomosis (٢٠.٩%) & anterior venous patch graft to elongate the anterior wall of the liver graft HVs in ٦ anastomosis (٨.٩%). The source of the venous grafts was the recipient’s PV in ١٤ venous grafts (٢٠.٩%), the recipient’s recanalised umbilical vein in ٢ venous grafts (٣%) & in one case (١.٥%) we used the recipient’s left external iliac vein (as interposition venous graft) & the donor’s inferior mesenteric vein (as anterior venous patch graft). Hepatic venoplasty in the form of widening of the hepatic vein opening, suturing of two HVs opening to be a single opening or anterior venous patch graft (only used in adult receoients) was used in ١٠ pediatric recipients and ١٢ adult cases. |