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العنوان
Synthesis of some new thiophenes with expected biological activity /
المؤلف
Fakhr Eldien, Hader Mohamed Farid Mohamed Elshahat.
هيئة الاعداد
باحث / Hader Mohamed Farid Mohamed Elshahat Fakhr Eldien
مشرف / Margret Mansour Girges
مشرف / Moged Ahmed Berghot
مشرف / Moustafa Ahmed Gouda
الموضوع
Aminothiophene. Sulphadimidine. Pyrazole. Naphthoquinone.
تاريخ النشر
2012.
عدد الصفحات
234 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الكيمياء
تاريخ الإجازة
1/1/2012
مكان الإجازة
جامعة المنصورة - كلية العلوم - Chemistry
الفهرس
Only 14 pages are availabe for public view

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Abstract

In this work we aimed to utilize of 2-aminothiophenes for the synthesis of some new compounds related to thiophenes which possess considerable synthetic and pharmaceutical interest.
The original compounds were confirmed by the spectral data and submitted for biological evolution.
Also, some of the synthesized azo dyes were applied on polyester fabrics and their color measurement and fastness properties were evaluated>
Synthesis of thiophene derivatives:
1- Synthesis of some new arylazo thiophene derivatives starting from 2-amino-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxamide (1)
2- Syntesize some new sulphadimidine derivatives incorporating thiophene moiety starting from 2-amino-4-phenylthiophene-3-carboxamide (11)
3- Synthesize some new pyrazole derivatives incorporating thiophene moiety starting from 2-aminothiophenes 23a-b and 1
4- Syntesize some new naphthoquinone derivatives incorporating thiophene moiety starting from 2-aminothiophenes 23a-b and 1.