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العنوان
Peripartum anesthetic management of parturient receiving anticoagulants
الناشر
Ahmed El sayed Yusif
المؤلف
Yusif , Ahmed El sayed
هيئة الاعداد
مشرف / Ashraf Ahmed Adel El masry
مشرف / Ahmed Ali Badawy
مشرف / .Mona Mostafa Lotfy
مشرف / Yusif , Ahmed El sayed
تاريخ النشر
2012
عدد الصفحات
111P.:
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الطب
تاريخ الإجازة
1/1/2012
مكان الإجازة
جامعة القاهرة - كلية الطب - anesthesiology
الفهرس
Only 14 pages are availabe for public view

from 107

from 107

Abstract

Classically, common therapies for thromboprophylaxis among pregnant females are heparin (either unfractionated and or low molecular weight heparin), vitamin K antagonists and antiplatelets. Recently, newer agents have been introduced into practice including danaporoids, direct thrombin inhibitors and fondaparinux. It should be noted that choice of antithrombotic agent during pregnancy is primarily based upon efficacy of antithrombotic agent to reduce maternal morbidity and mortality risks for associated condition with pregnancy and at the same time possess no or minimal inadvertent fetal and maternal complication. Unfractionated heparin has been used for decades for many indications during pregnancy. It is a large molecule, so it does not cross the placenta and thus, in contrast to the coumarin derivatives, does not cause teratogenesis or toxic fetal effects. Over the last 10 years LMWHs have become the preferred anticoagulants for treating and preventing thromboembolism in all patients. While comparative data are much less robust in pregnant patients, several series have confirmed the safety and efficacy of LMWHs in pregnancy