الفهرس 
coverOnly 14 pages are availabe for public view
 |  | from | 246 |  |  |
| | | from | 246 | | |
Abstract
The aim of the study was to evaluate the effect of Pentoxifylline
used in preparation of semen samples that will be used for
intacytoplasmic sperm injection (ICSI) in infertile men complaining
of mild and moderate asthenozoospermia in comparison to semen
samples without PTX preparation on the outcome of ICSI. The study
was carried out on 30 infertile patients where pentoxifylline was
used for semen processing prior to oocyte injection, another 30
infertile patients where no pentoxifylline was used in semen
processing and 60 infertile patients where crossing over of the semen
sample was done further subdividing it into 2 subgroups in which the
first half of the semen sample was incubated with pentoxifylline and
the second half of the sample was not incubated with pentoxifylline
and the wife’s oocytes were divided on these 2 samples. The results
showed that pentoxifylline has a significant positive effect on ICSI
outcome in cases of mild and moderate asthenozoospermia as
regards the fertilization rate, the embryos quality and the pregnancy
rates without any significant embryotoxic effect or significant
increase in the abortion rate. Moreover, the results are more solid
when using prospective crossing over of the semen sample in each
patient i.e. each patient acts as his own control