الفهرس 
INTRODUCTIONOnly 14 pages are availabe for public view
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Abstract
This work comprised a review of literature on the endometrium (normal, hyperplastic and cancerous). It stated the different patterns regarding the ultrasonography, histopathology, flowcytometry and oncogene expression.
The study was designed to evaluate the pattern of the endometrium in the different states using the different modalities of investigations in order to shed more light on the subject of endometrial carcinoma.
Evaluation was based on comparison between the different types of the endometrium regarding their ultrasonographic appearance, DNA flowcytometric study and the use of immunohistochemisty to evaluate the c-erb B2 oncogene expression.
The study was conducted on 50 patients presenting to Shatby Maternity University Hospital with abnormal uterine bleeding who have been selected from the outpatient clinic and inpatient wards. Twenty patients were having endometrial hyperplasia, another twenty with endometrial carcinoma while the last group (10 patients) were found to have normal endometrial).
The findings of the patients were recorded and the results were tabulated and subjected to statistical analysis. The mean values for the three different groups were found to be within the previously known values regarding different types of endometrial hyperplasia and cancer, the incidence of grade and stage for the malignant cases and also the values regarding endometrial thickness, proliferative index, S Phase Fraction, aneuploidy and oncogene expression. Correlations were found between SPF and ET and PI in the first groupand between SPF and Oncogene expression and ET and oncogene expression and proliferative index in the second group.
No correlation was found between the age of the patients and the different studied parameters. Also there was no correlation between the grade of the endometrial neoplasm and the studied parameters.
In the light of such results it is possible to recommend the use of the different studied parameters to evaluate the different cases of endometrial pathology to give more insight on the natural history of cases of endometrial hyperplasia and to try to probe the prognosis of cases of endometrial carcinoma.