الفهرس 
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Abstract
This study was carried out to evaluate the effect of two types of Saccharomyces cereviseae probiotics Diamond-v and Bakers’ yeast, on growth, immunity and digestive enzymes of Nile catfish, Clarias gariepinus . Fish were grouped into seven groups and fed a diet containing 0.0, 0.5%, 1% and 1.5% Diamond-v probiotic and 1.5%, 3% and 4.5% Baker’s yeast for 3 months. the results indicated that, the fish groups 1% Diamond-v and 3, 4.5% Baker’s yeast significant improved growth parameters (body Weight gain, feed conversion ratio, specific growth rate and condition factor) and histopathological picture of the intestine revealed marked increase in the length of intestinal villi, activation of the mucous secreting cells and colonization of yeast cells in the intestinal villi. No significant difference in hematological parameters in Diamond-v groups while, significant improvement in Baker’s yeast groups occurred. Biochemical parameters included SGPT, SGOT, Urea, Uric acid and Creatinine were improved in both groups, while significant increase in SGOT activity in Baker’s yeast groups. Total proteins and globulin also significantly improved. The both humeral and cellular non specific immunity were significantly increased in 1%Diamond-v and 3, 4.5% Baker’s yeast also, digestive enzymes included lipase, amylase and protease were increased at the same concentrations. from these results, we concluded that Saccharomyces cereviseae probiotics Diamond-v and Bakers’ yeast supplement is promising as an alternative method to antibiotics for disease prevention in catfish, and the optimum level of Diamond-v was 1% and for Baker’s yeast was 3% for optimum growth, feed utilization and immunity.