الفهرس 
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Abstract
The present study aimed to investigate the effect of Avocado fruit on serum lipid profile, kidney and liver function as well as histopathological changes of liver and kidney . Thirty male albino rats were used in this study. Rats were divided into five main groups (n=6 rats), group (1) was fed on basal diet and used as negative control. Group (2) fed on the hypercholesterolemic diet and used as positive control. Groups (3), (4) and (5) fed on the hypercholesterolemic diet supplemented with (2.5, 5 and 10%) dried avocado, respectively. At the end of experiment, blood samples were taken for biochemical analysis, while liver and kidney were removed for histopathological examination.
Results revealed that positive group had significant decreases in body weight gain (BWG) , Feed efficiency ratio (FER) and serum HDL-C and significant increased in serum levels of total lipid (TL), total cholesterol (TC), triglycerides (TG) , LDL-C ,
VLDL-C, uric acid (UA), blood urea nitrogen (BUN), creatinine (Cr) , AST and ALT compared to negative group. Hypercholesterolemic groups fed on different levels of avocado fruit had significant increased in food intake (except those treated with 2.5%), BWG, FER, and serum HDL-C while had significant decreased in serum levels of TL, TC, TG, LDL-c, VLDL-c, UA, BUN, Cr, AST and ALT compared to positive group. Conclusion, the present study concluded that Avocado fruit had beneficial effects on lipid profile and lipoprotein levels as well as it improved liver and kidney functions in hypercholesterolemic rats.