الفهرس 
Pediatric Bronchial AsthmaOnly 14 pages are availabe for public view
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Abstract
Serum samples were taken from sixty children whom were subdivided into four groups: group I (mild to moderate asthmatic cases), group II (severe asthmatic cases), group III (non-asthmatic wheezy cases) and group IV (controls) and the protocol for this study will be approved by the local ethics committee, and informed consent was obtained from the parents.
Serum YKL-40 levels was detected by ELISA kits supplied by (Metra™ YKL-40 EIA Kit-QUIDEL CORPORATION)
Results:
The results of our work showed that YKL-40 is a good screening test for asthma , with best cut off value (45 ng/ml) and sensitivity (89%) and is considered better negative test in prognosis as well with sensitivity (86.7%) , when its value below 90 ng/ml, it means better prognosis.
Conclusions:
The observed increase in serum concentrations of total YKL-40 suggest that measurements of it may be useful in monitoring asthmatic children and can be used as bimarker of asthma and may in assessment in degree of control of asthma