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Abstract considered a national problem since it infects about 60% of the inhabitants of egypt’ian villages . .disease and this is achieved through the preparation of some antigens as a ’,- r - I mea.p.s of immunological control. infected people. However until now, these are not enough to eliminate use of immune system in controlling this disease, aiming to produce a vacclne against Schistosomiasis. , The aim of the present study was to identify and characterize an immunogenic antigen which might may - be a candidate for vaccine In the present work soluble worm antigens of S. haematobium was applied to SDS- PAGE which show dif~erent molecular weight bands. - Western blotting was done which detected one immunogenic band. |