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Abstract Carbimazole is widely used drug but it has tcratogenic effects as it crosses the placenta Exogenous thyroxin given to mother during pregnancy was proved to has minimal placental crossing ability So, intrauterine injection of thyroxin is tried to protect the embryo from the hazardous effects of carbirnazole In this study twenty five adult pregnant female albino rats were used The rats were divided into two main groups .control and experimental |