الفهرس 
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Abstract
Human umbilical cord blood is collected from umbilical cord after childbirth. It is a rich source of stem cells, a variety of different stem cell types have been identified within HUCB; Hematopoietic stem cells mesenchymal stem cells, and endothelial stem cells.
Mesenchymal stem cells are multipotent stem cells that can differentiate into a variety of cell types, different mesodermal endodermal and ectodermal lineages. They represent a promising tool for cell therapy.
MSCs from UCB are more primitive than MSCs isolated from some other tissue sources. The immaturity of newborn cells is associated with lower immunogenicity and higher proliferative capacity compared to bone marrow-MSCs (BM-MSCs) which are known to undergo a
significant DROP in their cell number and proliferative/differentiation capacity with age.
Human umbilical cord blood (HUCB) as a source of MSCs has a number of significant advantages over other stem cell sources. First of all,
non-invasive collection without any risk for the donor, do not involve ethical issues and a real abundance worldwide make the HUCB a readily available source of stem cells. Furthermore, a rising number of public and private banks, which can store huge quantities of cord blood units, allow an optimal HLA match for the allogeneic or autologous transplantation.