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العنوان
Oral precancers /
المؤلف
El-Hakim, Mohammed Ahmed Abdallah.
هيئة الاعداد
باحث / Mohammed Ahmed Abdallah El-Hakim
مشرف / Nabil Abd El Aty El Morshedy
مشرف / El-Sharawy Kamal Mohamed
مشرف / Ahmed Musaad Abd El-Fattah
الموضوع
Mouth Neoplasms-- Therapy.
تاريخ النشر
2012.
عدد الصفحات
135 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الحنجرة
تاريخ الإجازة
1/1/2012
مكان الإجازة
جامعة المنصورة - كلية الطب - Ear Nose Throat
الفهرس
Only 14 pages are availabe for public view

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from 140

Abstract

Oral cavity cancer accounts for approximately 3% of all malignancies and is a significant worldwide health problem.
Examination of oral cavity is very important to give an idea about the general condition of oral cavity. But oral examination alone cannot always distinguish benign from premalignant and malignant lesions.
Oral premalignant lesions are defined as a morphologically altered tissue in which cancer is more likely to occur than in its apparently normal counterpart and classified into two main categories: precancerous Lesionsand Precancerous Conditions. The malignant transformation rates range from 1 to 19% .
Precancerous Lesion can be defined as a benign lesion with morphologically altered clinical or histopathological tissue which has greater than normal risk of containing microscopic focus of cancer or of transforming into malignant lesion after diagnosis at a later date.These precancerous lesions include leukoplakia, erythroplaika, and the palatal lesions of reverse smokers and Actinic Cheiloses.
Precancerous Condition can be defined as a disease or patient habit which does not necessarily alter the clinical appearance of local tissue but is known to have a greater than normal risk of precancerous lesion or cancer development. The precancerous conditions include Dyskeratosiscongenita, submucous fibrosis, lichen planus ,epidermolysisbullosa, and discoid lupus erythematous, Plummer-Vinson syndrome and xerodermapigmentosa.
Screening techniques for oral precancers include: Biopsy and Cytology ,Oral Exfoliative Cytology: Liquid-Base Preparations and Conventional Smears in Oral Lesions ,Cytomorphometry: Computer-Assisted Analysis Brush Biopsy ,Clinical Tissue Staining Technique, Chemiluminescence Technique ,Light Emission Technique ,Tissue autofluorescence–based systems (VELscope) and Imaging.