الفهرس 
CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD)Only 14 pages are availabe for public view
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Abstract
Chronic obstructive pulmonary disease (COPD) is defined by
progressive, irreversible airflow limitation and an inflammatory
response of the lungs, usually to cigarette smoke. However, COPD is
a heterogeneous disease in terms of clinical, physiological, and
pathological presentation. The aim of the study is to measure the
diffusion capacity in the different stages of COPD. The pathological
hallmarks of chronic obstructive pulmonary disease (COPD) are
inflammation of the small airways (bronchiolitis) and destruction of
lung parenchyma (emphysema). The functional consequence of
these abnormalities is airflow limitation. As regards the whole
sample, there was a statistically significant negative (inverse)
correlation between TLCO%, TLCO/VA, PCO2 and HCO3 and there
was a statistically significant positive (direct) correlation between
TLCO%, TLCO/VA, PO2 and Sat O2 .There was a statistically
significant positive (direct) correlation between FVC%, FEV1%,
FEF25%, FEF50%, FEF75%, TLCO% and TLCO/VA .There was a
statistically significant difference between high resolusion CT
findings in mild, moderate and very severe COPD.
Key Words:
COPD-Diffusion capacity of carbon monoxide-Spirometery-
Arterial blood gases- High resolution CT.