الفهرس 
IntroductionOnly 14 pages are availabe for public view
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Abstract
Renal ischemia-reperfusion (I/R) injury is the major cause of ARF. It occurs in various clinical settings including severe hypotension and subsequent resuscitation, shock, sepsis, renal transplantation, and aorto-vascular surgery.In a trial to assess the cardiac lesions following acute renal I/R in male and female rats, and to show if there are gender differences in the development of these lesions, , the present study was conducted on 70 adult albino rats. At the end of the experimental protocol, serum samples were used to determine urea, creatinine, lactate dehydrogenas , and creatine kinase levels; while cardiac samples were used to determine lipid peroxide, glutathione reductase, superoxide dismutase, and catalase levels.The results of this study show that:
1-Acute renal I/R injury causes deterioration in renal functions as well as cardiac lesions.
2-Female rats are more protected from the renal and cardiac lesions following acute renal I/R injury than male rats.
3-Estrogen decreases the cardiac lesions following acute renal I/R.