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Abstract Neonatal sepsis is still a major cause of morbidity and mortality in the neonatal care units. In our study there was decrease in the blood culture proven sepsis cases compared to previous studies in Kasr El-Aini Hospital and other centers but we couldn’t conclude that there was a real improvement of infection control measures because of the significant higher percentage of culture proven late onset sepsis. Nosocomial infection that is infection which neither is neither present nor incubating at birth. It has been recognized as a major problem in intensive care units. A variety of factors probably contributes to this alarming infection including over crowding, invasive diagnostic and therapeutic procedures and impaired host defenses especially in low birth weight infants. The aim of this study was to determine the microbiological pattern of bacterial infection in NICU in EI-Minia University hospital on admission or during incubation, to determine the risk factors, antimicrobial susceptibility profile of the isolated organisms and to correlate the clinical data with the laboratory data. This study was carried out in the neonatal intensive care unit (NICU) in EI-Minia University Hospital from November 2006 to May 2007. |