الفهرس 
Neonatal hyperbilirubinemiaOnly 14 pages are availabe for public view
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Abstract
Jaundice in near-term and term newborns is clinically evident in over 60% of newborns during the first week after birth.
While hyperbilirubinemia (TSB>1.0 mg/dL) occurs in nearly all infants, significant hyperbilirubinemia (TSB>12.9 mg/dL) and excessive hyperbilirubinemia (TSB values above the 95th percentile for age in hours) occur in only 5% to 6% of the healthy newborn population.
During the 1990s, jaundice was the most frequent reason for readmission after early hospital discharge.
Kernicterus has been described in a small subset of these infants. For these reasons, early identification of newborn infants at risk for developing severe hyperbilirubinemia and possible bilirubin induced neurologic dysfunction has become a public health issue.
Early discharge of healthy term newborns after delivery has become a common practice for either medical, social or economic reasons. However, an association between the decreased length of stay and the risk of readmission to the hospital has been shown and the most common cause for readmission during the early neonatal period is hyperbilirubinemia. It is difficult to predict which infants are at increased risk for significant and relatively late hyperbilirubinemia, and there is an obvious need to implement follow up programs or to develop predict confidential guidelines that will enable the physicians to predict or to identify which of the early discharged newborns will develop significant hyperbilirubinemia .
An accurate noninvasive measure of TSB would be useful, because it would minimize blood sampling for a frequent and usually benign clinical condition.
In addition, an accurate, noninvasive test might allow cost-effective implementation of a risk-based universal bilirubin screening program and follow-up to prevent the unexpected occurrence of severe hyperbilirubinemia and perhaps even kernicterus.
Some of non invasive measures are in accurate such as visual assessment and others frequent follow up over two days every 6 hours which may be difficult with early discharge.
The present study was conducted to evaluate the accuracy of transcutaneous bilirubin measurement for initial assessment of neonatal jaundice
This study was conducted on 100 newborn infants with clinically apparent jaundice who otherwise appear healthy either preterm or full-term, presented to the NICU of Maternity and Children Hospital of Ain Shams University.
checking transcutaneous bilirubin (TcB) measurement within 30 minutes of withdrawal of serum samples using a Minolta/AirShields Jaundice Meter (JM).
The newborns were divided into 2 groups according to the onset of jaundice :
• Group A : include neonates with jaundice in the first week of life.
• Group B : include neonates with jaundice starting after the first week of life.
Our results shows that TcB is significantly correlated to TSB in all included neonates irrespective to gestational age, sex, body weight, postnatal age and mode of delivery.