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العنوان
The effects of curcumin and pioglitazone on streptozocin-induced diabetic nephropathy in rats /
المؤلف
El-Sayed, Amaal Nabil Sadek,
هيئة الاعداد
باحث / Amaal Nabil Sadek El-Sayed
مشرف / Mohamed Mahmoud Sayed Ewais
مشرف / Cherine Maurice Khalil
مشرف / cHERRY kAMEL NASR
الموضوع
pharmacology.
تاريخ النشر
2012.
عدد الصفحات
120p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
علم الأمراض والطب الشرعي
تاريخ الإجازة
1/1/2012
مكان الإجازة
جامعة قناة السويس - كلية الطب - الفارماكولوجى
الفهرس
Only 14 pages are availabe for public view

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Abstract

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Summary and conclusion
Diabetic nephropathy is a major cause of morbidity in diabetic patients

and it is a leading cause of end-stage renal disease. Its incidence is
increasing worldwide.
There is an increasing demand by patients to use a natural product with
anti-diabetic activity, because insulin and oral hypoglycaemic drugs possess
undesirable side effects .
...•. ,
In this study therapeutic action of curcumin on (STZ)-induced diabetic
nephropathy in rats in comparison to Pioglitazone (as an example for oral
hypoglycemic drug) was studied.
We expected that curcumin might have a therapeutic effect on
Streptozotocin-induced diabetic nephropathy in rats similar to that of
pioglitazone.
Results of the study showed that groups treated with only curcumin
showed no improvement in any parameter except for anti-oxidants, which
were affected significantly with curcumin.
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