الفهرس | Only 14 pages are availabe for public view |
Abstract Leptospirosis is an infectious zoonotic disease that affects wild and domestic animals as well as human. It occurs worldwide but it is most common in tropical and subtropical areas with high rainfall. Many surveys proved that the disease is present in Egypt. It is caused by pathogenic bacteria called leptospira. Leptospires belong to the genus leptospira, family Leptospiraceae, order Spirochaetales. The phenotypic classification of leptospires to pathogenic (L. interrogans), and non-pathogenic (L. biflexa), has been replaced by a genotypic one, in which 16 genomospecies include all serovars of both groups. Leptospires are highly motile, helical, obligate aerobic spirochetes that share features of both gram-positive and gramnegative bacteria. They are about 0.25 × 6-25μm in size, characterized by its sharp, tapering, hooked ends. They grow in simple media enriched with vitamins (B1 and B12), long-chain fatty acids and ammonium salts with an optimum growth temperature of 28 to 30°C. |