الفهرس 
Introdution and Review of literatureOnly 14 pages are availabe for public view
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Abstract
Periodontitis is one of the most common diseases of humans, it is an infectious condition that can result in inflammatory destruction of periodontal ligament and alveolar bone which can persist in the absence of treatment and result in exposure of periodontium. The invasion of inflammation to bone surface initiate bone loss.
The goal of bone regeneration procedures is to facilitate the growth of new bone into osseous defects such as those encountered in periodontal disease. Materials that are used in bone regeneration therapy should, therefore, support the attachment and proliferation of the bone forming osteoblastic cells.
In the present study, Bonit matrix which is one of the synthetic bone grafts has been tried as bone substitute for 12 patients with chronic periodontitis in comparison with other 12 patients treated with modified widman flap. The clinical parameters were recorded at baseline, 3 months, 6 months and 9 months after surgery.
In all patients of the two groups, the probing depth decreased significantly by the end of the study. But in the Bonit matrix treated group, a clinically significant decrease in probing depth was observed at end of the study (5.2±0.64 mm to 2.0±0.3mm) rather than MWF group which were (6.1±0.44 mm to 3.7±0.33mm) All patient showed clinical attachment gain (CAL) from baseline to the end of the study in group II (6.6±0.49 mm to 3.2±0.2mm)in group I (7.2±0.33 mm to 4.6±0.23mm).
But group II only showing significant bone density change (124.7±5.2 to 135.4±3.2)
It is concluded that Bonit matrix bone material can be used for healing of intrabony periodontal defect rather than modified widman flap alone as it increases bone fill % at end of the study. It is easy to handle and it causes no hypersensitivity or any negative effect on human tissues as a bone grafting material.