![]() | Only 14 pages are availabe for public view |
Abstract The use of antibiotics in animal agriculture has helped in the production of safer animal products, improving growth rate, and conserving feed and water resources. The use of drugs in food animals is fundamental to animal health and well-being as well as to the economics of the industry. Though antibiotics use has its advantages, the intensive and extensive use of antibiotics has lead to the emergence of antimicrobial resistance. A total number of 140 Oreochromis niloticus with an average body weight (20±0.09g) were allocated into seven groups, each group had two replicates (10 fish replicate”), G 1 was regularly fed with basal diets; G 2, 3 were regularly fed basal diet supplemented with oxytetracycline at concentration of 100, 150 mg /kg diet respectively. While G 4, 5 were regularly fed basal diet supplemented with florfenicol at concentration of 5, 10 mg /kg body weight respectively and G 6, 7 were fed basal diet supplemented with amoxicillin at concentration of 70, 80 mg/kg body weight. Feeding rate 5% from total weight. The diet was given two times daily. The food was applied by hand in corresponding pond. The fish of each group were weighted every two weeks during the experimental period for adjustment of feeding requirements of each group and determination of growth parameters. Clinical signs, postmortem lesions, histopsthological changes and antibiotic residues in fish tissues were recorded at the end of experiment (12weeks). Blood samples were taken from fish at the end of the experiment to determine some biochemical parameters. |