الفهرس 
Anatomy of the StomachOnly 14 pages are availabe for public view
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Abstract
The present work studies the effect of verapamil and ranitidine on indomethacin induced gastric ulcers in albino rats. The volume and pH of gastric secretion was estimated and histopathological examination was done.
It was found that indomethacin induced gastric ulcers were significantly reduced by verapamil. This decrease was duration dependent. There was no significant difference between this effect and that produced by ranitidine.
On the other hand, when both verapamil and ranitidine were used together, it was found that there was a significant reduction in the mean ulcer score and histopathological changes compared to that induced by verapamil or ranitidine alone. Gastric acidity and volume of gastric secretion showed significant reduction in the same manner to mucosal changes.
Also, indomethacin and ranitidine increased the gastric motility induced by acetylcholine. whereas, verapamil decreased the gastric motility. When ranitidine and verapamil were used together there was a decrease in gastric motility in small doses and an increase in gastric motility in large doses.