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العنوان
ROLE OF ANTIBODY IMMUNREACTIVITY IN
DIAGNOSIS OF PRIMARY AND SECONDARY
HEPATIC ADENOCARCINOMAS/
الناشر
MONA MAGDY MOHAMEd،
المؤلف
MONA MAGDY ،MOHAMED
هيئة الاعداد
باحث / MONA MAGDY ،MOHAMED
مشرف / ALI FOAD ،EL- HINDAWI.
مشرف / AHMED MAHMOUD ،ABD EL-HADI.
مشرف / SAMIA MOHAMMED ،GABAL.
تاريخ النشر
2012.
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
علم الأورام
تاريخ الإجازة
1/1/2012
مكان الإجازة
جامعة القاهرة - كلية الطب - الباثولوجى
الفهرس
Only 14 pages are availabe for public view

from 126

from 126

Abstract

Vysis LSI 4q12 Tri-Color Rearrangement Probe through
Fluorescent In Situ Hybridization (FISH) test has been used
to estimate the c-Kit gene expression aberrations
/rearrangements among the five hepatic
adenocarcinomas of cancer stem cell origin cases (CK19
+ve/c-Kit +ve /CK18 +ve /CD133 +ve cases). from data
analysis it has been found that the c-Kit amplification or
aberrant gene patterns whether separate or combined
together or combined with abnormal one tricolor gene
expression are the most common aberration
/rearrangement . This finding is coming with the strong
and moderate immunohistochemistry expression of c-Kit
and CD133 in those five hepatic adenocarcinomas of
cancer stem cell origin cases (CK19 +ve/c-Kit +ve /CK18
+ve /CD133 +ve cases.
Key word
Primary - secondary- hepatic-ICC- Ck1-HCC- adenocarcinomas