الفهرس 
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Abstract
The aim of the present work was to study spontaneous bacterial peritonitis in patients with cirrhotic ascites and the role of ascitic fluid lactoferrin in diagnosis of spontaneous bacterial peritonitis.
For this purpose, all patients were subjected to the following Thorough history taking, Complete clinical examination and Full investigations including: Complete blood count and ESR, Liver function tests, Serological tests for viral hepatitis markers: - HBsAg. – HCV Ab Kidney function tests (urea and creatinine), abdominal ultrasonography and diagnostic abdominal paracentesis. The ascitic fluid was subjected to the following Physical examination, Biochemical examination, Cell count, Direct microscopic examination, Microbiological cultures and Measurement of ascitic fluid lactoferrin AFLAC Statistical analysis of the presenting data revealed :
• no significant difference between studied groups as regard age and sex.
• Abdominal pain , fever, poor response to diuretics and encephalopathy were main presenting symptoms in patients with SBP. Moreover hematemesis and melena were evident in SBP patients prior to hospital admission.
• Clinical evidences of cirrhosis , portal hypertension and hepatic decompensation by ascites were present in both groups.
• No significant difference between studied groups as regard CBC while there was highly significant increase in ESR in SBP group .
• No significant difference between studied groups as regard ALT, AST and PT while there was significant increase in serum total bilirubin and serum creatinine in SBP group .
• HCV infection was the main etiology of liver cirrhosis in both groups while HBV infection was much less common. HCV & HCV coinfection was present in 20 % of SBP group.