الفهرس 
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Abstract
Several studies have indicated that the incidence and prevalence of allergic diseases are increasing. It is well known the effect of pollution in allergic diseases and blood gases, but the detection of sputum and nasal discharge gases in allergic patients was not evaluated till now.
Therefore, this study was intended to help in diagnosis of asthmatic and rhinitis patients and detection of blood, nasal , sputum gases by employing, Po2, Pco2, pH, skin test, specific IgE (house dust, pollens, tobacco and moulds), eosinophils count and PEFR.
The examined individuals were classified into the following groups:
Group I: 30 allergic asthma, the patients aged from 15 to 50 years, 12 males and 18 females.
Group II: 30 allergic rhinitis, the patients aged from 15 to 50 years, 16 males and 14 females.
Group III: 30 control persons were selected with no history or symptoms suggesting chronic allergic diseases. Aged from 15 to 50 years, 15 males and 15 females.
For each patient or normal subject, the following investigations were conducted:
1- Clinical Studies:
This included complete data on medical history taking, special habit, work place, duration, contact with animals, season of attack, economic case. Also physical examinations were performed by the physician in the clinic.
2- Routine Investigations:
- Complete urine analysis.
- Complete stool analysis.
- Kidney function tests (Urea and Creatinine).
- Liver function tests (Billirubin, SGOT, and SGPT).
- Blood sugar test (Random sample).
- Chest and paranasal sinus X-ray.
3- Skin prick test.
4- Specific IgE to house dust,mixed moulds,mixed pollens and tobacco tests.
5- PEFR (peak expiratory flow rate).
6- Eosinophilic count.
7- Measurment of Gases in blood, sputum and nasal discharge.
As regards the confirm of diagnosis of asthmatic patient by elevating of specific IgE, eosinophilic count (in sputum and blood), Pco2 (sputum) and decreased of PEFR and Po2 (blood).
In case of group II (rhinitis group), elevated of eosinophilic count in nasal discharge and blood and mild elevated of specific IgE, Pco2 (nasal secretion), mild decrease of PEFR and Po2 (blood). This can help in differensiate the diagnosis of asthma and rhinitis .There was elevated allergic data in smokers group than non-smokers group. So, pollution by dust, pollens, moulds and tobacco smoke making a risk in allergic patients.
In conclusion, this study suggests using sputum and nasal discharge in diagnosis of asthma and rhinitis by employing PO2, PCO2, pH, Eosinophilis count, specific IgE beside PEFR. Also, the risk of smoking and pollution on allergic patients.