الفهرس | Only 14 pages are availabe for public view |
Abstract Obstructive jaundice is a common clinical condition which may be associated with potentially life - threatening complications Better, (1980). It is widely accepted that there is an increased incidence of renal impairment in jaundiced patients, however, there seems to exist a controversy as to the nature and the mechanism of these renal complications (ilishida et aL, 1982 and 0, Neill et a!., 1991). Epstein (1986) reported that the derangements in renal function commonly complicate disorders of the liver. These complications include decreased renal blood flow and glomerular filteration rate, and sodium retention. Also, Oms et a!. (1991) demonstrated the same renal impainnent in common bile duct ligated rabbits. Moreover, O’Neill et a!. (1991), reported that the decrease in creatinine clearance after common bile duct ligation in experimental animals was accompanied by a decrease in urinary sodium excretion. However, Better and Massry (1972) and Mon et a!. (1982) reported that there are no significant changes in glomerular filtration rate and renal plasma flow in conunon bile duct ligated animals. Allison et a!. (1978) did not observe any sodium retention in jaundiced rats after ligation of the biliary tract and Ilishida et a!. (1980). |