Introduction
Xanthones of Gentianaceae
Iridoids and secoiridoids of Gentianaceae
Aim of Work
Review of literature
Biological Review
Chemical Review
Taxonomy
Materials, apparatus and techniques
Materials
Apparatus and Equipments
Techniques
Phytochemical hytochemical study for C. spicatum aerial and root parts and C. pulchellum root
Preliminary phytochemical screening of C. spicatum aerial and root parts and C. Pulchellum root
Extraction, fractionation and isolation for constituents of C. spicatum aerial and root parts and C. pulchellum root
Biologically - guided fractionation study for C. spicatum aerial and root parts and C. Pulchellum root
Suppression of the Inflammatory Cytokines (TNF-?)
Free radical scavenging activity (DPPH antioxidant assay)
Identification of compounds isolated from the n-butanol fraction of C. spicatum aerial part
Cytokine inhibitory compounds
Identification of cytotoxic compounds isolated from the n-butanol fraction of C. spicatum aerial parts
Study of the cytotoxicities of the isolated xanthones against cultured HeLa, THP-1 and HL-60 cells lines (compounds 7, 11, 13)
CYP3A4 inhibition activity of xanthones isolated from the nbutanol fraction of C. spicatum aerial parts (comp. 7, 8, 11, 12, 13)
Identification of the compounds isolated from the n-butanol fraction of C. spicatum root
Identification of compounds having CYP3A4 inhibition activity
CYP3A4 inhibition activity of the isolated xanthones from the n-butanol fraction of both C. spicatum aerial and root parts
CYP3A4 mRNA express ion in the HepG2 cell line
Identification of the compounds isolated from the n-butanol fraction of C. pulchellum root
Identification of compounds having antihepatotoxic activity
رAntihepatotoxic effect of some secoiridoid compounds isolated from C. spicatum aerial and root parts and C. Pulchellum root (compounds 15, 18, 19 and 32)
General summary and conclusion
Preliminary phytochemical screening of C. spicatum aerial and root parts and C.pulchellum root
Extraction, fractionation and isolation of constituents from C. spicatum aerial part, C. spicatum root and C. pulchellum root
Biologically guided fractionation study for C. spicatum aerial part, C. spicatum root and C. pulchellum root
References
الملخص العربي
الفهرس 
