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Abstract Our results indicated that swine eradication strategy had a significant impact on the reduction of positive HPAI H5N1 cases of poultry backyards, and human population. However, there was no significant impact of the swine eradication on poultry farms. The reorganization of swine colonies and its transfer to desert border will progressively improve the HPAI situation and provide more safety to the human and poultry raising industry. The Egyptian governorates must be built-in a potent statistical system to record the right numbers of swine population and other needed statistical surveys. Also, the backyard flocks are more exposed to HPAI H5N1than farm poultry. Using the available H5 poultry vaccines alone in Egypt were not effective in advance to control the disease. So, restrictive biosecurity, quarantine, and vaccination programs must be applied at poultry farms and backyards to control the zoonotic transmission of HPAI H5N1 and to keep our poultry industry safe. |