الفهرس 
SUPERVISORSOnly 14 pages are availabe for public view
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Abstract
Remineralization as a treatment procedure has received great attention both from clinicians as well as researchers. Fluoride and casein phosphopeptide-amorphous calcium phosphate are known to inhibit demineralization and enhance remineralization.
The Objective of this study was to assess enamel remineralization, both in vivo and in vitro, in permanent teeth of children, after application of two types of CPP-ACP, with and without fluoride (CPP-ACPF and CPP-ACP), using two regimens of application, with and without iontophoresis.
The study consisted of in vivo and in vitro parts:
- In vivo study: One hundred and twenty permanent teeth, in healthy children, aged 7-10 years were selected. The teeth showed non-cavitated, smooth surface, white enamel lesions, showing readings: 15-20, with the DIAGNOdent. The teeth were divided into two groups of 60 teeth each. group I was treated for five minutes, for five consecutive days (regimen I), while group II was treated for five minutes, for ten consecutive days (regimen II). Both groups were further subdivided into four subgroups (15 teeth each), according to the remineralizing agent used and application of iontophoresis (subgroups IA and II A: CPP-ACPF, without iontophoresis, subgroups IB and II B: CPP-ACPF, with iontophoresis, subgroups I C and II C: CPP-ACP, without iontophoresis and subgroups I D and II D: CPP-ACP, with iontophoresis). After remineralization, the degree of remineralization was evaluated, using the DIAGNOdent. Two follow up visits were performed, after one and three months, to assess the degree of de- or remineralization of the treated teeth.
- In vitro study: The sample consisted of 80 extracted sound premolars, free from caries, cracks or any developmental defects. The teeth were assigned to two groups of 40 teeth each. group I was treated for five minutes, for five consecutive days (regimen I), while group II was treated for five minutes, for ten consecutive days (regimen II).