الفهرس 
Chapter I: LITERATURE REVIEWOnly 14 pages are availabe for public view
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Abstract
The present study demonstrates an unprecedented green process for the synthesis of spherical shaped and stabilized Ag NPs using Monascus purpureus supernatant via two methods; Non-irradiated and irradiated condition.
The objective of the study can be achieved in three main sections:
Part I describes the factors affecting M. purpueurs pigments production and silver nanoparticles synthesis.
Part II of the research involves the silver nanoparticles synthesis by M. purpueurs supernatant without gamma irradiation.
Part III of the research involves the silver nanoparticles synthesis by M. purpueurs supernatant under gamma irradiation effect.
In Part I, the main achievements and key factors affecting M. spurpueurs pigments production were discussed.
A sequential optimization strategy based on statistical experimental designs was employed to enhance the production of M.purpueurs pigments. Plackett-Burman design was used to screen the bioprocess parameters which significantly influencing M. purpueurs pigments production.
In Part II, AgNO3 Aqueous solution was treated with M. purpureus supernatant for synthesis of silver nanoparticles (Ag-NPs). The Nano metallic dispersions were characterized by surface Plasmon absorbance measuring at 420nm for Ag Nanoparticles. Transmission electron microscopy, Dynamic light scattering (DSL) approved particle size in rang from 1nm up to 8nm. XRD analysis of the silver nanoparticles confirmed the formation of metallic silver. Further analysis was carried out by Fourier Transform Infrared Spectroscopy (FTIR), which indicated
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abounding of silver Nanoparticles with M.purpureus supernatant molecules and provides evidence for the presence of proteins as possible biomolecules responsible for the capping agent who helps in increasing the stability of the synthesized silver nanoparticles and EDX Spectra confirmed the presence of Nano crystalline silver. This small synthesized silver nanoparticles size it showed antibacterial and antifungal activities.
In Part III Aqueous dispersion of highly stable silver nanoparticles were synthesized using gamma irradiation of M.purpureus supernatant molecules as reducing and stabilizing agent. The size of the silver nanoparticles can be turned by controlling the radiation dose and mixing method of AgNO3 solution with M. purpureus supernatant (irradiation process).The obtained Ag nanoparticles were stable for over 3 months at room temperature.