الفهرس 
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Abstract
Patients with refractory epilepsy appear to have a higher risk for seizure-related cardiac abnormalities. H-FABP testing offers a number of theoretical and practical advantages for the detection of myocardial injury. The aim of this study was to evaluate ictal changes in H-FABP serum levels among paediatric patients with intractable epilepsy in comparison to their levels in the same population in the inter-ictal period and to those of healthy - matched control subjects.
Twelve patients with intractable epilepsy (having 20 seizure episodes-2 seizure episodes were recorded in 8 patients) and 15 healthy-matched subjects were studied. Serum levels of H-FABP were significantly increased in the patient group in both the inter-ictal (901.7 + 437.9) and the ictal phase (1725.0 + 1401.3) compared to their values in the control group (481.3 + 86.1). However, levels of H-FABP in the patient group were not significantly different in the ictal phase (1725.0 + 1401.3) compared to their levels in the inter-ictal phase (901.7 + 437.9). Statistical correlations between Chalfont severity score , duration of illness and duration of seizure recorded of the patients and H-FABP levels in both inter-ictal and ictal phases were not significant .
Thus we conclude that elevated serum levels of H-FABP may indicate a form of chronic myocardial ischemia in our studied patients. Moreover, It is possible that the small number of the patients in our study and the nature of the intractable epilepsy disorders may explain the lack of possible effects of any of the correlated parameters in our study.