الفهرس 
ObesityOnly 14 pages are availabe for public view
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Abstract
Obesity is an increase of the total body fat
and occurs as the result of the imbalance between
energy expenditure and caloric intake. This
imbalance has been thought to be under genetic
and environmental influence (Arner, ٢٠٠٠). In
recent years, we have begun to realize that adipose
tissue is more than just a passive depot for excess
energy (Ahima and Flier, ٢٠٠٠). Indeed, as several
studies have shown, adipose tissue is a
metabolically active tissue that expresses and
secretes a large number of proteins. Such
molecules, called adipocytokines, have a hormonelike
action and interfere with basal and glucose
metabolism (Bouret and Simerly, ٢٠٠٤, Hoffstedt
et al., ٢٠٠٤, Valsamakis et al., ٢٠٠٤, Voros et al.,
٢٠٠٤).
Epidemiologic and clinical data show that
obesity is associated with an increased risk of
cardiovascular disease, hypertension, type II
diabetes (Benzi, et al., ١٩٩٩), dyslipidemia, and
other metabolic diseases. Therefore, it is generally
agreed that obesity also is associated with
increased morbidity and mortality, and that this
increased health risk is positively correlated with
regional fat distribution, not simply .